Игорь Иванович
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Этонитазен . По эйфории он непревзойден !
J Med Chem
. 1975 Mar;18(3):318-20.
doi: 10.1021/jm00237a024.
J Med Chem
. 1975 Mar;18(3):318-20.
doi: 10.1021/jm00237a024.
Etonitazene. An improved synthesis
F I Carroll, M C Coleman- PMID: 237125
- DOI: 10.1021/jm00237a024
Abstract
1-(BETA-Kiethylaminoethyl)-2-(p-ethoxybenzyl)-5-nitrobenzimidazole (u, etonitazene) is a potent analgesic that has value in drug addiction studies. We have developed a simple high-yield synthesis of 1 that is adaptable to alrge scale preparations. The synthesis involves the condensation of 2-(beta-diethylaminoethylamino)-5-mitroaniline and p-ethoxyphenylacetic acid in Thf in the presence of EEDQ.Вложения
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